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NUNII’s Expert Pigment Corrector brings breakthrough innovation to skin pigmentation control

NUNII’s Expert Pigment Corrector brings breakthrough innovation to skin pigmentation control

NUNII is extremely proud to announce the launch of the Expert Pigment Corrector patient version, the ideal product for patients seeking a skin lightening cream which can be used at home, on daily basis, long term.

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NUNII’s active participation in IMCAS this year

NUNII’s active participation in IMCAS this year

For the first time, NUNII took an active part in the 22nd edition of IMCAS (International Master Course on Aging Science), the international trade fair for aesthetic surgeons and dermatologists, which this year took place from January 30th to February 1st 2020 at the Palais des Congrès in Paris.

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10 beauty tips for a healthy winter skin

10 beauty tips for a healthy winter skin

The effects of winter sunshine and winter temperatures are not to be taken lightly: especially since many people underestimate their impact on the skin.

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Once more, the use of illegal skin lightening creams highlights the dangers of Hydroquinone

Once more, the use of illegal skin lightening creams highlights the dangers of Hydroquinone

A recent study conducted in Brussels, which was published in the Journal of Skin Pharmacology and Physiology, has highlighted the serious dangers of hydroquinone penetrating the blood stream by skin absorption with a cumulative toxic effect with daily applications.

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Purchasing Depigmenting Products Online or on the Fly: Risky Business

Purchasing Depigmenting Products Online or on the Fly: Risky Business

It’s never been easier to buy cosmetic products online or on the fly, on street corners, but this often opens the door to all kinds of uncertainties and may even lead to jeopardize our health with products that escape any form of control.

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Dr BOCOUM, a reputed dermatologist, gives informed perspectives on his profession and the challenges he faces in his practice.

Dr BOCOUM, a reputed dermatologist, gives informed perspectives on his profession and the challenges he faces in his practice.

French dermatologist Dr Thierno BOCOUM is a happy professional because he gets to help many patients with the skin pigmentation problems.

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Intimate area pigmentation problems: NUNII is successfully addresses such issues thanks to their range of gentle skin lightening products

Intimate area pigmentation problems: NUNII is successfully addresses such issues thanks to their range of gentle skin lightening products

NUNII is known for the quality products it markets to medical physicians and dermatology professionals.

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Special focus and feedback on common skin disorders, and how to best deal with them

Special focus and feedback on common skin disorders, and how to best deal with them

Throughout one’s lifetime most of us will be affected at some point or by some form of skin problem.

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THE FUTURE APPEARS BRIGHTER

THE FUTURE APPEARS BRIGHTER

TH E UNIQ – WHITE ® SYSTEM is a unique professional system used exclusively by dermatologists and doctors and clinically proven to treat lentigo, melasma and skin spots.

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Meeting Mrs Sylvie BONDU, NUNII’s regional sales manager for the Paris region: her feedback on the current national and Int’l trends

Meeting Mrs Sylvie BONDU, NUNII’s regional sales manager for the Paris region: her feedback on the current national and Int’l trends

Interview with industry expert Mrs. BONDU, who is reporting the latest trends in skin pigmentation problems, health consequences of skin pigmentation, as well as the solutions of NUNII.

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NUNII receives the French JEI Label, an innovation certification for young enterprises

NUNII receives the French JEI Label, an innovation certification for young enterprises

A few weeks ago, NUNII obtained the French JEI Label (Jeune Entreprise Innovante) which in English signifies “A Young Innovative Company”.

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NUNII is filing for several new patents

NUNII is filing for several new patents

Thanks to a close partnership with the French INSERM and intense work, NUNII embarks on a series of new patent registrations.

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NUNII Laboratoire “The Game Changer in Depigmenting treatments” is expanding and forging a strong reputation in our home market

NUNII Laboratoire “The Game Changer in Depigmenting treatments” is expanding and forging a strong reputation in our home market

Launch of NUNII Laboratoire products into France.

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The five major health marketing trends to follow in 2019 and beyond

The five major health marketing trends to follow in 2019 and beyond

In recent years health marketing has gained growing importance in medical sectors.

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How to determine the strength of facial peels: debunking the myths and to determine how strong different peelings really are

How to determine the strength of facial peels: debunking the myths and to determine how strong different peelings really are

Much is being said and written today about how skin peeling treatments act on our skin.

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Are chemical peelings safe for dark skin types ?

Are chemical peelings safe for dark skin types ?

Chemical peelings have long proven efficacy in the pigmentation’s treatment disorders and photo aging, unfortunately studies evaluating the risks and side effects for patients with dark skins have been very limited to date.

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When cutting-edge research meets an innovative dermo-cosmetics company

When cutting-edge research meets an innovative dermo-cosmetics company

Recent research currently conducted by French INSERM researcher Céline GAUDEL, in partnership with French company NUNII Laboratoire, holds promising results in skin depigmentation treatment.

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Nunii’s international expansion on the Polish dermatology market

Nunii’s international expansion on the Polish dermatology market

The International Congress of Aesthetic & Anti-Aging Medicine in Poland was the perfect timing to introduce NUNII’s scientific expertise in pigmentation treatments.

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Special focus on the 2018 edition of the Skin of Color Update

Special focus on the 2018 edition of the Skin of Color Update

The 2018 Skin of Color Update : again this year, the not to be missed event took place in the US dermatology events calender which featured leading dermatology practitioners with their latest research and treatment techniques for skins of color.

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Effects of urban air pollution on the skin

Effects of urban air pollution on the skin

Airborne pollutants in urban areas : the scope of their detrimental effects on our skin.

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Nunii is one of the players in the world of dermo-cosmetics

Nunii is one of the players in the world of dermo-cosmetics

Nunii treatments are just one of the solutions patented dermatologists or specialized physicians can use with their patients to treat pigmentation problems : treatment protocol combinations are also possible.

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Glutathione : a new high-risk skin depigmentation agent

Glutathione : a new high-risk skin depigmentation agent

How Glutathione, an antioxidant recently being used for its skin-lightening properties, can reveal downright dangerous to consumer health.

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“To do or not to do” depigmenting treatments during the summer months

“To do or not to do” depigmenting treatments during the summer months

Attitudes to doing depigmentation treatments in warm weather varies among different populations and cultures across the world.

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Discovering and understanding children’s main hyperpigmentation problems

Discovering and understanding children’s main hyperpigmentation problems

Troubles in children’s skin pigmentation and skin tone evenness : a true problem for some young children and their parents.

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KANEBO’s hypo-pigmentation scandal : lessons to be learned

KANEBO’s hypo-pigmentation scandal : lessons to be learned

Not all skin depigmenting products are created equal.

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10 useful tips to protect your skin from the sun with the summer coming up

10 useful tips to protect your skin from the sun with the summer coming up

The first risk factor of the sun is to ignore the danger.

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An interview with “Franck CHUZEL”, a French endocrine disruptor expert

An interview with “Franck CHUZEL”, a French endocrine disruptor expert

The vision from a leading international expert on how skin brands must rebuild confidence with consumers today.

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Going back to the roots of NUNII Laboratoire

Going back to the roots of NUNII Laboratoire

A special interview with NUNII co-founder : François MONTCRIOL

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AMWC Taiwan 2018 : a landmark event for the booming Asian market

AMWC Taiwan 2018 : a landmark event for the booming Asian market

On the occasion of the edition of AMWC Asia, let’s go back to the incredible growth of aesthetic dermatology in this part of the world.

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NUNII takes proactive measures to avoid endocrine disruptors (EDCs)

NUNII takes proactive measures to avoid endocrine disruptors (EDCs)

NUNII’s ethical commitment to limit endocrine disruptors (EDCs) in its products.

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Nunii’s involvement in Corporate Social responsibility is going stronger than ever

Nunii’s involvement in Corporate Social responsibility is going stronger than ever

nunii Laboratoire bases its development on a responsible policy.

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Marketing dermo cosmetics : the race to lure the consumers will never end

Marketing dermo cosmetics : the race to lure the consumers will never end

Many laboratories overstrain marketing techniques to sell more cosmetics. We reveal some of them.

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Monaco AMWC : special focus on patient safety this year

Monaco AMWC : special focus on patient safety this year

Patient safety, recognized as a problem of global importance, was the main theme of the AMWC 2018 conference.

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The growing importance of social networks in the world of dermo-cosmetics

The growing importance of social networks in the world of dermo-cosmetics

nunii Laboratoire invests in digital strategy to communicate with doctors and patients worldwide.

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NUNII presents at Dubaï World Dermatology Congress

NUNII presents at Dubaï World Dermatology Congress

This month nunii Laboratoire makes its inaugural launch in the Middle East, North Africa and South Asia at Dubai World Dermatology & Laser Conference & Exhibition 2018.

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NUNII supports the sustainable economic development of rural communities in Madagascar

NUNII supports the sustainable economic development of rural communities in Madagascar

How the harvest of Centella asiatica for NUNII LABORATOIRE contributes to the education and improvement in living standards of 2,500 Malagasy families.

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French Public Investment Bank : a important sponsor and supporter of NUNII

French Public Investment Bank : a important sponsor and supporter of NUNII

French Public Investment Bank is strongly backing NUNII Laboratoire in the expansion of its activities.

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Meeting with Niamh COGAN

Meeting with Niamh COGAN

A moment with Niamh COGAN, President of nunii Laboratoire, on the occasion of International Women’s day.

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NUNII was present at the 20th IMCAS PARIS and the 21st SIES ITALY

NUNII was present at the 20th IMCAS PARIS and the 21st SIES ITALY

IMCAS celebrated its 20th Anniversary at the Leading Edge of International Innovation and in Bologna the 21st SIES, marked the official launch of NUNII Italia !

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NUNII is making its mark in the booming aesthetic medicine industry in Turkey

NUNII is making its mark in the booming aesthetic medicine industry in Turkey

nunii Laboratoire formalizes its launch in Turkey on the occasion of the Istanbul Estetik Forum.

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Avoiding controversial ingredients in depigmenting creams

Avoiding controversial ingredients in depigmenting creams

How to avoid controversial or irritating ingredients ? What you need to know to make the best choice for skin whitening products.

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NUNII has been awarded by the ‘Réseau entreprendre’

NUNII has been awarded by the ‘Réseau entreprendre’

NUNII has been selected by a French start-up “booster” organization to support its development.

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Patient’s share their exciting transformation with UNIQ WHITE SYSTEM

Patient’s share their exciting transformation with UNIQ WHITE SYSTEM

NUNII Laboratoire embarked on a series a of user-case studies with volunteers patients following the in vivo study of the UNIQ WHITE SYSTEM.

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6 Must-know tips for choosing a depigmenting cream

6 Must-know tips for choosing a depigmenting cream

How to safely lighten your complexion and reduce the appearance of dark spots.

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Melasma : causes, effects and solutions

Melasma : causes, effects and solutions

Pigmentation is the most frequent motive for dermatological consultations in many countries.

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Looking back on 2017 and a focus on NUNII’s projects for 2018 !

Looking back on 2017 and a focus on NUNII’s projects for 2018 !

2017 was a memorable year for nunii Laboratoire ! Now, let’s look at the horizon 2018 which promesses many exciting events !

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The sun: our friend or foe ?

The sun: our friend or foe ?

What do you really know about the effects of the sun exposure ?

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Blue Light (HEV Light) : friend or foe ?

Blue Light (HEV Light) : friend or foe ?

Recent findings have identified HEV, or blue light, as being harmful to our skin and eyes.

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The ‘Journées Dermatologiques de Paris’

The ‘Journées Dermatologiques de Paris’

The JDP is one of the most cutting-edge dermatology congresses worldwide.

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NUNII partnership with INSERM

NUNII partnership with INSERM

“The quality of the partnership has enabled the teams to push the boundaries in the current knowledge regarding melano-genesis.”

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Global growth of aesthetic medicine is in full swing

Global growth of aesthetic medicine is in full swing

Focus on the major changes of the medical aesthetics market.

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Looking back on 18 months of business Incubation

Looking back on 18 months of business Incubation

The incubator played a vital facilitating role in the development of NUNII.

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The NUNII ‘expert Day’ workshop in Romania and the National Congress of Dermatology, Brasov : a special focus

The NUNII ‘expert Day’ workshop in Romania

More than one thousand dermatologists from all over the world gathered to share their experiences and expertise.

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NUNII Laboratoire has obtained the French « INPI Talent » certification

NUNII has obtained the « INPI Talent »

NUNII was honored with the prestigous national “INPI Talent” award for its innovation !

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October 2017 was host to milestone events in the world of dermo-cosmetics

Milestone events in the world of dermo-cosmetics

Presentation of the three important events of the dermo-cosmetics in october.

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NUNII LAUNCHES IN THE UK : a true success

Nunii launches in the UK

On September 16th last, NUNII Laboratoire proudly launched on to the UK market.

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Transform your skin and regain a glowing complexion after the summer

Transform your skin after the summer

After a busy or relaxing summer, this is the best possible time to care about your skin.

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A satisfied NUNII Laboratoire user, Marine A. : “Hoping for a brighter future”

Marine A. : “Hoping for a brighter future”

“It really gave my confidence a boost, finally there was hope and a light at the end of the tunnel.”

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Welcome to the NUNII Laboratoire Blog !

Welcome to the NUNII Blog

It is with great pleasure that we welcome you to our new Blog on the NUNII Laboratoire website.

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© 2023 Nunii Laboratoire

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Bibliography:
1. Abdel-Malek Z; Suzuki I; Tada A; Im S; Akacali C. The melanocortin-1 receptor and human pigmentation. Ann N Y Acad Sci. 199 Oct 20;885:117-33
2. Abdel-Malek Z; Scott MC; Suzuki I; Tada A; Im S; Lamoreux L; ito S; Barsh G; Hearing VJ. The melanocortin-1 receptor is a key regulator of human cutaneous pigmentation.. Pigment Cell Res. 2000;13 Suppl 8:156
3. Bertolotto C; Busca R; Ballotti R; Ortonne JP. L’AMP cyclique est un régulateur de la pigmentation de la peau.médecine/sciences 2001 ;17 :177-85
4. Buscà R1, Ballotti R. Cyclic AMP a key messenger in the regulation of skin pigmentation. Pigment Cell Res. 2000 Apr;13(2):60-9.
5. Cheli Y, Ohanna M, Ballotti R, Bertolotto C. Fifteen-year quest for microphtalmia-associated transcription factor target genes. Pigment Cell Melanoma Res. 2010 Feb;23(1):27-40.
6. Christina Wasmeier, Alistair N. Hume, Giulia Bolasco1 and Miguel C. Seabra. Melanosmes at a glance. Journal of Cell Science 2008;121,3995-3999
7. Corine Bertolotto, Karine Bille, Jean-Paul Ortonne, and Robert Ballotti. Regulation of Tyrosinase Gene Expression by cAMP in B16 Melanoma Cells Involves Two CATGTG Motifs Surrounding the TATA Box: Implication of the Microphthalmia Gene Product The Journal of Cell Biology, Volume 134, Number 3, August 1996 747-755.
8. Costin GE, Hearing VJ. Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J. 2007;21:976–94. [PubMed]
9. Fistarol SK, Itin PH. Disorders of pigmentation. J DtschDermatolGes. 2010;8:187–201. [PubMed]
10. Jiri Vachtenheim1 and Jan Borovansky´ ‘‘Transcription physiology’’ of pigment formation in melanocytes: central role of MITF. Experimental Dermatology, 19, 617–627
11. Lin JY, Fisher DE. Melanocyte biology and skin pigmentation. Nature. 2007;445:843–50. [PubMed]
12. Park HY, Kosmadaki M, Yaar M, Gilchrest BA. Cellular mechanisms regulating human melanogenesis. Cell Mol Life Sci. 2009;66:1493–506. [PubMed]
13. Plensdorf S, Martinez J. Common pigmentation disorders. Am Fam Physician. 2009;79:109–16. [PubMed]
14. Rouzaud F, Kadekaro AL, Abdel-Malek ZA, Hearing VJ. MC1R and the response of melanocytes to ultraviolet radiation. Mutat Res. 2005;571:133–52. [PubMed]
15. Thody.AJ; Graham.A; Does alpha-MSH have a role in regulating skin pigmentation in humans?. Pigment Cell Res, 1998 Oct; 11(5):265-74.
16. Wang N1, Hebert DN. Tyrosinase maturation through the mammalian secretory pathway: bringing color to life. Pigment Cell Res. 2006 Feb;19(1):3-18.
17. Yamaguchi Y, Hearing VJ. Physiological factors that regulate skin pigmentation. Biofactors. 2009;35:193–[PMC free article] [PubMed]
18. Xufeng Wu, Blair Bowers, Kang Rao, Qin Wei, and John A. Hammer III. Visualization of Melanosome Dynamics within Wild-Type and Dilute Melanocytes Suggests a Paradigm for Myosin V Function In Vivo. The Journal of Cell Biology, Volume 143, Number 7, December 28, 1998 1899-1918

Bibliography:
1. Ortonne JP, Passeron T. Vitiligo and other disorders of hypopigmentation. In: Bolognia JL, Jorizzo JL, Schaffer JV, eds. Dermatology. 3rd ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 66.
2. Jazienicka Iwona, Katarzyna Kozlowicz, Anna Sokolowska, Jolanta Kwiatek. Phototoxic and photoallergic reactions after cosmetics: Department of Cosmetology and Aesthetic Medicine Medical University in Lublin Poland, Clinic and Department of Gynecology and Gynecologic Endocrinology Medical University in Lubin Poland.
3.CIR (Cosmetic Ingredient Review Expert Panel) Final report on the safety assessment of t-butyl hydroquinone. 1986.Journal of the American College of Toxicology 5, pp. 329–351.
4.Findlay, G. H., Morrison, J. G. L., & Simson, I. W. (1975). Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams. British Journal of Dermatology, 93(6), 613-622.
5.Cardinali G, Kovacs D, Picardo M. Mechanisms underlying post-inflammatory hyperpigmentation: lessons from solar lentigo. Ann Dermatol Venereol. 2012 Dec;139 Suppl 4:S148-52. doi: 10.1016/S0151-9638(12)70127-8. Review. PubMed PMID: 23522630.
6. Lamel SA, Rahvar M, Maibach HI. Postinflammatory hyperpigmentation secondary to external insult: an overview of the quantitative analysis of pigmentation. Cutan Ocul Toxicol. 2013 Mar;32(1):67-71. doi: 10.3109/15569527.2012.684419. Epub 2012 Jun 6. Review. PubMed PMID: 22667459.
7. Callender VD, St Surin-Lord S, Davis EC, Maclin M. Postinflammatory hyperpigmentation: etiologic and therapeutic considerations. Am J Clin Dermatol. 2011 Apr 1;12(2):87-99. doi: 10.2165/11536930-000000000-00000. Review. PubMed PMID: 21348540
8. Davis EC, Callender VD; Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. J Clin Aesthet Dermatol. 2010 Jul 3(7):20-31.
9. Arora P, Sarkar R, Garg VK, et al; Lasers for treatment of melasma and post-inflammatory hyperpigmentation. J Cutan Aesthet Surg. 2012 Apr 5(2):93-103. doi: 10.4103/0974-2077.99436.
10. Rossi AB, Leyden JJ, Pappert AS, et al; A pilot methodology study for the photographic assessment of post-inflammatory hyperpigmentation in patients treated with tretinoin. J Eur Acad Dermatol Venereol. 2011 Apr 25(4):398-402. doi: 10.1111/j.1468-3083.2010.03798.x.
11. Nestor M, Bucay V, Callender V, et al; Polypodium leucotomos as an Adjunct Treatment of Pigmentary Disorders. J Clin Aesthet Dermatol. 2014 Mar 7(3):13-7.

Bibliography:
1. UVA & UVB, The Skin Cancer Foundation; Published on May 24, 2013 Medical Reviewers John H. Epstein, MD Stephen Q. Wang, MD.
2. World Cancer Research Fund / American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. Washington DC: AICR 2007, Part Two-Chapter7, p244.
3. Artificial tanning devices: public health interventions to manage sunbeds. Geneva: World Health Organization; 2017, 2.1 p12
4. Solar ultraviolet radiation: global burden of disease from solar ultraviolet radiation / Robyn Lucas … [et al.] ; editors, Annette Prüss-Üstün … [et al.]. (Environmental burden of disease series ; no. 13.) World Health Organization 2006.
5. 11th Annual EWG sunscreen guide-Environmental working Group. http://www.ewg.org/sunscreen/report
6. Cosmetic Chemistry Paperback – Virtual Beauty Corporation November 1, 2009, Florence Barrett-Hill, ISBN-13: 978-0473124670 Chapter 1 Sun protection actives & Actions